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Each state has a law that allows pharmacists to substitute less expensive generic drugs for many brand names. However, if your doctor specifies that a brand name must be dispensed, then the pharmacist may not substitute the generic. Sometimes an acceptable generic is available that your doctor may not be aware of.
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A limited distribution network is a pharmaceutical distribution technique that some drug companies have capitalized upon to impede generic and biosimilar competition.
Some drug companies nonetheless use REMS to justify access restrictions via LDNs.
A common false impression is that LDNs are required as part of FDA Risk Evaluation and Mitigation Strategies (REMS); actually, they are not.
The FDA, in October, confirmed that it was investigating however has but to problem a comment or findings.
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