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What is Hae disease? Hereditary angioedema (HAE) is caused by a low level or improper function of a protein called the C1 inhibitor. With HAE, the blood vessels are affected. An HAE attack can result in rapid swelling of the hands, feet, limbs, face, intestinal tract, larynx (voicebox), or trachea (windpipe). How do you know if you have angioedema? As well as visible swellings, angioedema can cause other symptoms, including: a hot or painful sensation in the swollen areas. swelling of the inside of the throat, the windpipe and the tongue, making breathing difficult. How long does swelling from allergic reaction last? In general, angioedema lasts longer than urticaria, but the swelling usually goes away within 24 hours. Symptoms include deep swelling around the eyes and lips, and sometimes swelling of the genitals, hands, and feet. Occasionally, severe and prolonged swelling of the tissue can be disfiguring.
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